alexa Zika Virus Infection: New Findings Related to Neurological Complications
ISSN: 2167-0897

Journal of Neonatal Biology
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Zika Virus Infection: New Findings Related to Neurological Complications

Diandra Martins e Silva1*, Monara Kedma Nunes1, Valécia Carvalho1, Fernanda Sousa1, Cláudio Ventura2, Silmar Teixeira1 and Victor Hugo Bastos1

1Brain Mapping and Functionality Laboratory (LAMCEF/UFPI), Federal University of Piauí, Brazil

2Department of Biomedicine of Federal University of Piauí, Brazil

Corresponding Author:
Diandra Caroline Martins e Silva
Universidade Federal do Piaui, Brazil
Tel: + 308-865-8441
E-mail: [email protected]

Received April 27, 2016; Accepted May 05, 2016; Published May 10, 2016

Citation: Silva DME, Nunes MK, Carvalho V, Sousa F, Ventura C, et al. (2016) Zika Virus Infection: New Findings Related to Neurological Complications . J Neonatal Biol 5:219. doi:10.4172/2167-0897.1000219

Copyright: © 2016 Silva DM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Zika virus infection has attracted attention of the world population, being reported in many countries / territories. The Zika vírus (ZIKV; genus Flavivirus, family Flaviviridae) is a pathogen globally transmitted by emerging mosquitoes (arboviruses) of the genus Aedes spp. Recently in Brazil, the Ministry of Health confirmed the association between ZIKV and microcephaly outbreak in the Northeast, however, is not clear in the studies the pathogenesis of this process, which led us to conduct a review in databases Pubmed, Medline and Lilacs. The literature reports that the clinical manifestations of ZIKV infection are very similar to infections such as dengue and chikungunya, but usually milder and without deaths, however, the absence of specific commercial serological tests for ZIKV, makes infection a clinical challenge in diagnosis. The association of ZIKV with microcephaly is initially related to the first three months of pregnancy and leads to neurological complications that when does not result in death, causes severe functional limitations accompanied by changes in neuropsychomotor development. Because of the increased number of cases of microcephaly associated with ZIKV infection reported in Brazil, further discussions should be carried out.


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