Adnexal tumors are growths that form on the organs and connective tissues around the uterus in women. Adnexal tumors are most often noncancerous (benign), but they can be cancerous (malignant).Adnexal tumors occur in the Ovaries, Fallopian tubes, Connective tissue around the ovaries or fallopian tubes. Diagnosis of adnexal tumors involves a careful physical exam, imaging tests and, sometimes, surgery. Treatment for adnexal tumors depends on the specific location and types of cells involved
The pathophysiology is not well understood for most adnexal masses; however, some theories have been proposed. Functional cysts may be the result of variation in normal follicle formation. Mature cystic teratoma may be the result of abnormal germ cell proliferation. Endometriomas are thought to result from retrograde menstruation or coelomic metaplasia. The exact cause of epithelial neoplasms is unknown, but recent studies have suggested a complex series of molecular genetic changes is involved.
For people below 65 years of age the leading causes of mortality were somewhat different in terms of their relative importance . Cancer was the most prominent cause of death within this age group averaging a standardised death rate of 82.7 deaths per 100 000 inhabitants in the EU-28 in 2012 followed by diseases of the circulatory system. Contrary to the data for the whole of the population, diseases of the respiratory system did not figure among the three most prevalent causes of mortality for those aged less than 65: for example, the standardised rate for diseases of the respiratory system was lower than the death rate for suicide. EU-28 death rates for persons aged less than 65 fell between 2004 and 2012 for each of the main causes of death shown in Figure 6. This was particularly the case for transport accidents and ischaemic heart diseases, where the incidence of death fell by 42.8 % and 28.6 % respectively.