Deep vein thrombosis, or deep venous thrombosis, (DVT) is the formation of a blood clot (thrombus) within a deep vein, predominantly in the legs. Non-specific signs may include pain, swelling, redness, warmness, and engorged superficial veins. DVT often develops in the calf veins and "grows" in the direction of venous flow, towards the heart. When DVT does not grow; it can be cleared naturally and dissolved into the blood (fibrinolysis).
Disease Statistics: Postal self-administered questionnaires about VTE prophylactic methods practiced by Polish neurologists were sent to 218 neurological wards where stroke is treated. If no response was received, the questionnaire was faxed and finally we attempted to obtain information by telephone. One hundred and seventy-six (80.7%) stroke centers of 218 responded. The majority (137/176; 77.8%) of centers had a stroke unit. The median admission rate of surveyed wards was estimated to be 320 patients/year (range from 20 to 1000 patients/year). The most common method of VTE prophylaxis reported was low molecular weight heparin (LMWH) (98.9%), and the least common was intermittent pneumatic compression (IPC) (6.8%).
The basic treatments for the disease are Anticoagulation, which prevents further coagulation, home treatment, stockings, walking, and repeat imaging and IVC filters, thrombolysis, and thrombectomy. The aims of the physicians are to prevent clot becoming larger, clot becoming lose and traveling to lungs, new clot formation and Post thrombotic syndrome.
Major Research on Disease
The current major research on the diseases are efficacy of low doses of heparin for the prevention of the DVT after a major surgery, accuracy of the clinical assessment for DVT, Decreased plasma levels of activated factor VII in patients with deep vein thrombosis etc.