Pathophysiology: Herpes B virus is an alpha herpes virus that is particularly enzootic (endemic in animals) in the rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) members of the macaque genus, Macaca (as seen in the image below). Among the nonhuman-primate herpesviruses, only herpes B virus is clearly able to cause disease in humans.
Treatment: The case was that of a 29-year-old laboratory worker ("W.B.") who developed fatal meningoencephalitis and transverse myelitis following a bite on the hand from a seemingly healthy rhesus monkey. Herpes B virus infects a broad range of mammalian and avian species, including New World monkeys, Old World monkeys, and humans. Most infected macaques are asymptomatic. When symptoms do occur, they are very similar to those caused by HSV.
Statistics: Analysis from a total of 19,362 accumulated cases, it was found that 13,004 cases with full local information presented in 682 counties (cities) of 29 provinces (cities, municipalities) in China. The World Health Organization (WHO) lists Herpes B virus as a neglected tropical disease. It estimates that about 50 million people worldwide have Herpes B virus in the world and that it causes about 50,000 deaths each year.