Addiction is defined as repeated use of a psychoactive substance or substances, to the extent. Nicotine addiction is the fundamental reason that individuals persist in using tobacco products, and this persistent tobacco use contributes to many diseases. Smoking is primarily practiced as a route of administration for nicotine through the lungs; it is a way of getting nicotine into your system rapidly. In assessing the nature of tobacco smoke, scientists must consider chemical composition, concentrations of components, particle size, and particle charge. Long-term exposure to nicotine produces biologic adaptations leading to reduced sensitivity to some of the effects of nicotine and symptoms of distress soon after cessation of drug use .
Nicotine replacement therapy increases the chances of stopping smoking by 50 to 70%. Adding behavioural support (in person or via telephone for at least four sessions of contact) to nicotine replacement therapy increases the chances of stopping smoking by a further 10 to 25%. Bupropion and nortriptyline aid long-term smoking cessation in adults, but other antidepressant medications do not. However, adding bupropion or nortriptyline to nicotine replacement therapy does not provide an additional long-term benefit. Among current smokers there were 46.3% people with strong nicotine dependence, while in the group of ex-smokers the corresponding proportion was 10.8%.In most of the patients studied, the level of ND was high or very high. The prevalence of heavy smoking for long periods was high in our sample.