Osteomalacia is a condition associated with bone-deformity due to inadequate mineralization in growing bones . While some cases relate to hereditary syndromes, renal disease, or use of medication, rickets in the world mostly stems from nutritional insufficiency Indeed, the lay press has lamented the pain, deformity, and disability due to Osteomalacia. Approximately 107,000 new fragility fractures; number of people aged 50+ with osteomalacia, approximately 520,000; economic burden of new and prior fractures € 1,486 million each year; by 2025 burden will increase by 23 % to more than € 1.8 billion (€ 1,828 million).
Hip fractures account for nearly as many hospital days as acute myocardial infarction and for more than prostate and breast cancers combined Without medical management, rachitic leg-deformities can persist and worsen. Effective management of rachitic children begins with an appropriate diagnosis. When osteomalacia is biologically active, curative therapy is needed. Doses of vitamin D for treatment are much higher than the doses needed to prevent rickets. When rickets is due to vitamin D deficiency, treatment may be initiated with vitamin D