Transient amnesic syndromes are striking clinical phenomena that are commonly encountered by physicians in acute medical settings.Diagnosis of such syndromes can be challenging, and their causes have been debated for over 50 years. • Winbeck et al found a significant incidence (10/28) of acute DWI changes in patients with TGA, which is comparable to the TIA group (21/74).
Although the patients who presented with a TIA had a higher prevalence of vascular risk factors, those in the TGA group (who had DWI changes) were found to have significantly more carotid atherosclerosis. The incidence has been estimated 10.2 per 100,000 per annum. Once transient global amnesia (TGA) is diagnosed, provide reassurance to the patient and schedule at least one follow-up visit with a neurologist.