Typhoid fever is an infection that causes diarrhea and a rash. It is most commonly due to a type of bacterium called Salmonella typhi(S. typhi). In the year 2006, 5 cases of Typhoid fever were reported in Poland. Recent epidemological studies shown that there is lower incidence of Typhoid fever in Poland compared to other countries. Prevalence rate of 0.0% was reported in Poland.
Pathophysiology is After the ingestion of contaminated food or water, the Salmonella bacteria invade the small intestine and enter the bloodstream temporarily. The bacteria are carried by white blood cells to the liver, spleen, and bone marrow. The bacteria then multiply in the cells of these organs and reenter the bloodstream.Researches occured on Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine and Commonly Administered Vaccines after Co-administration, Molecular subtyping of Salmonella enterica serovar Typhi isolate.