Pathophysiology: Hepatitis refers to an inflammatory disease which is mainly affects liver. Viral hepatitis is classified as A, B, C, D, E and G. Hepatitis viruses cause liver damage. Inflammation happens throughout liver and hepatocytes are destroyed by cytotoxic cytokines and natural killer cells. Cellular necrosis occur but liver usually able to repair itself and regain complete function if no other complications occur. There are three phases: Prodromal phase, Icteric phase and Recovery phase.
Disease Statistics: Viral hepatitis is most often registered infectious disease in the world. Most of the cases have been recorded of Hepatitis A in Poland with increase in number till 1993 and decreased abruptly after that. Deceasing trend was observed in Hepatitis B as well as C.
Treatment: Intravenous rehydration is given as supportive care but no specific emergency treatment is recommended as such. Patients are admitted in conditions of severe complications. Evaluation for hepatic encephalopathy is done. Certain patients may benefit from pharmacologic therapy. Patients are advised to avoid prolonged or vigorous physical exertion until their symptoms improve and maintain adequate hydration.
Research: The study was presented in 2002 by Department of Epidemiology, Medical University of Lublin. Other prominent institute working in this field includes Department of Preventive Medicine, University of Medical Sciences, Poznan.