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3-Nitro-2-(trihalomethyl)-2H-chromenes In Reactions With 1,3-Dipoles: Synthesis And Cytotoxic Activity Of ∆3-Annulated Chromane Derivatives | 73987
ISSN: 2161-0444

Medicinal Chemistry
Open Access

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3-Nitro-2-(trihalomethyl)-2H-chromenes in Reactions with 1,3-Dipoles: Synthesis and Cytotoxic Activity of ∆3-Annulated Chromane Derivatives

2nd International Conference on PHARMACEUTICAL CHEMISTRY

Vladislav Yu Korotaev, Nikolay S Zimnitskiy, Igor B Kutyashev, Alexey Yu Barkov and Vyacheslav Ya Sosnovskikh

Ural Federal University, Russia

ScientificTracks Abstracts: Med Chem (Los Angeles)

DOI: 10.4172/2161-0444-C1-033

The [3+2] cycloaddition of sodium azide and stabilized azomethine ylides to 3-nitro-2-(trihalomethyl)-2H-chromenes 1 and 2 was studied and cycloadducts 3‒8 were synthesized.

Korotaev V Yu graduated from the Ural State University in 1993 and has completed his PhD in 1998. Currently he works at the Department of Organic Chemistry of the Ural Federal University as a senior researcher. He has published more than 65 papers in peer-reviewed journals. His area of scientific interests includes unsaturated nitro compounds, heterocyclic compounds and fluoroorganic chemistry.