alexa A Novel SERS-based Approach To Detect Hydrogen Peroxide Scavenging Activity | 18873
ISSN: 2155-6210

Journal of Biosensors & Bioelectronics
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

3rd International Conference and Exhibition on Biosensors & Bioelectronics

Weiping Qian, Qingfeng Chen, Yanying Rao and Xiaoyuan Ma
Accepted Abstracts: J Biosens Bioelectron
DOI: 10.4172/2155-6210.S1.022
Abstract
The importance of evaluating the antioxidant activity has been widely reported in the past two decades not only for the extensive application of antioxidants in food industry and food nutriology, but also because of the discoveries of the strong correlations between reactive oxygen species (ROS) and many pathogenesis of human diseases, e.g. nervous system injuries, atherosclerosis and cancer. Hydrogen peroxide (H2O2), a key part of ROS, is generated in vivo under physiological conditions by peroxisomes (a kind of oxidative enzyme including glucose oxidase and D-amino acid oxidase) and superoxide dismutase which catalyze the dismutation of superoxide radicals. Along with superoxide anion radical, H2O2 can damage many cellular components and further convert into more ROS such as hydroxyl radical. Thus, the evaluation of H2O2 scavenging activity is an important part for assessing the ROS scavenging activity. Generally, the evaluation of H2O2 scavenging activity is peroxidase based or enzyme-free but biomarker dependent. Many methodologies based on different mechanisms have been developed for detecting H2O2 and/or H2O2 scavenging activity, e.g. chemiluminescence, fluorometry, colorimetry, cyclic voltammetry, electro spin resonance, etc. Surface-enhanced Raman Scattering (SERS) is a new powerful analytical technique with ultrahigh sensitivity. In addition to the ??whole-finger-prints?? information and the low water background, SERS has high signal enhancement and fluorescence quenching effects, which are extremely desirable for the biological sample analysis. Because of its unique attributes, SERS has been used in a wide range of fields, including homeland security, food safety, clinical diagnosis, trace detection, chemical and biochemical monitoring, etc., since it was discovered in the late 1970s. In this work, a novel SERS-based approach to detect H2O2 scavenging activity by using gold nanoshell precursor nanocomposites (SiO2/ GNPs) as nanoprobes is developed. Compared with conventional methods, the novel SERS-based method presented here with high sensitivity, rapid determination, relative ease of measurement may serve as an additional means for estimating the activities of multifunctional antioxidants.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7