alexa A Reliable Characterisation Of Eugenol An Anti-diabetic Constituents From Plant Myristica Fragrans By Analytical Technique
ISSN: 2329-6836

Natural Products Chemistry & Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

2nd International Conference and Exhibition on Marine Drugs and Natural Products
June 15-17, 2017 London, UK

Mohamad Taleuzzaman, Sadaf Jamal Gilani and Mohd. Aamir Mirza
Glocal University, India
Fulvic Limited, New Zealand
Posters & Accepted Abstracts: Nat Prod Chem Res
DOI: 10.4172/2329-6836-C1-014
Abstract
Today, there is a so many demand of herbal medicine in the global market but due to scarcity of authentic data regarding the parameters and methods employed for assessing the quality of medicines Myristica fragrans Houtt. Eugenol is present in many aromatic plants. It is reported 320 ppm is present in the seed of Myristica fragrans. It contains an active principle of drug identified and quantifies by chromatography method, and its structure was established by spectroscopic methods. To assess the quality of raw materials, proximate parameters like ash values (total ash, acid insoluble ash and water soluble ash), loss on drying and foreign matter were determined using standard pharmacopoeial methods as per WHO guidelines. A stock solution of Eugenol (1000μg/ml) was prepared by dissolving 10 mg accurately weighed Eugenol in methanol and diluting it to 10 ml of methanol. From this stock solution, a calibration curve is developed with a dilution series in range of concentration 0.2μg/ml -10μg/ml. From UV-Spectroscopy λmax determined and it is found to be 278-280 nm by scanning 200-400 nm. For method development study prepared three quality control dilutions, samples of 2, 6 and 8μg/ml were prepared for studying precision, accuracy and ruggedness. Eugenol belongs to a class of phenyl propanoids (C10H12O2). The IUPAC name of the compound is 4-Allyl-2-methoxyphenol having molecular mass 164.2g/mol with pKa=10.19 at 25°C. Apart from anti-diabetic properties, reported other pharmacological properties like hypocholesteremic, anti-inflammatory, anti-diarrheal, chemo preventive action, etc. and hence there is a great need to determine the amount of eugenol present in the different extracts. In vivo diabetic mice model studies with eugenol showed reduction in blood glucose levels by 38% likely due to inhibition of α-glucosidase while insulin and glycated hemoglobin levels remain unchanged. Diabetes Mellitus (DM) is a metabolic disorder of multiple etiologies characterized by elevated levels of blood glucose resulting from defects in insulin production. The proposed characterisation is helpful for further study in instrument like HPLC and LC-MS/MS.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version