Journal of Bacteriology & Parasitology

Accuracy of the Kato-Katz method in diagnosis of the diagnosis of S. mansoni and soil transmitted helminths infection in Zimbabwe

3^rd International Congress on Bacteriology and Infectious Diseases

August 04-06, 2015 Valencia, Spain

Nyandoro George

Posters-Accepted Abstracts: J Bacteriol Parasitol

Abstract:

There has been evidence in inference variations from small samples sizes to huge sample sizes so is sensitivity and specificity
of diagnostics tools with different samples. We evaluated the Kato-Katz technique in the absence of a gold standard using
Bayesian modeling for the determination of S. mansoni and soil transmitted helminths infection (STHs) in Zimbabwe. This
is a secondary analysis based on primary school children (n=15 818) aged 10-15 years who were enrolled in the national
mapping of S. mansoni and STHs. A Bayesian approach was used to evaluate the diagnostic performance of the evaluation
tool. The fomol ether diagnostic technique was generally more sensitive with S. mansoni detection operational characteristics
as follows (Sensitivity: 0.995; 95% Bayesian Credible Interval (BCI): 0.989-0.999), STHs-Hookworm detection (Sensitivity:
0.991; 95% BIC; 0.988-0.993), STHs-A. lumbricoides detection (Sensitivity: 0.992; 95% BCI;0.989-0.995) and STHs-T. trichiuria
(Sensitivity: 0.988 95% BCI: 0.926-1.00); then the Kato- Katz diagnostic technique (for S. mansoni detection (Sensitivity: 0.981;
95% BCI:0.971-0.994), STHs-Hookworm detection (Sensitivity: 0.966; 95% BCI;0.963-0.970), STHs-A. lumbricoides detection
(Sensitivity: 0.967; 95% BCI; 0.974-0.981) and STHs-T. trichiuria (Sensitivity: 0.988; 95% BCI; 0.974-0.981). However, specificity
is higher for the Kato- Katz technique compared to the fomol ether concentration technique. The fomol ether concentration
technique has better performance compared to the Kato-Katz technique and have increased the number of primary school
children who need treatment in the field compared to recommended the Kato- Katz technique alone.