alexa Active Case Finding For Pulmonary Tuberculosis And Detection Of Drug Resistance Among HIVinfected Patients In Gondar, Ethiopia
ISSN: 2155-9597

Journal of Bacteriology & Parasitology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

2nd International Congress on Bacteriology & Infectious Diseases
November 17-19, 2014 DoubleTree by Hilton Hotel Chicago-North Shore, USA

Martha Alemayehu, Baye Gelaw, Ebba Abate, Abraham Aseffa, Liya Wassie, Yeshambel Belyhun, Shiferaw Bekele, Russell R. Kempker , Henry M. Blumberg
Accepted Abstracts: J Bacteriol Parasitol
DOI: 10.4172/2155-9597.S1.008
Abstract
Background: Patients co-infected with HIV and TB often lacks the classic symptoms of pulmonary TB thus making TB diagnosis difficult. Current practice is to wait for symptomatic persons to present for TB screening, which can result in a delayed diagnosis of TB and consequently continued transmission in the community. The global HIV epidemic may be contributing to increase in MDR-TB prevalence. Objective: To determine the prevalence of undiagnosed pulmonary TB cases through active case finding including MDR-TB, among HIV-infected patients. Methods: A cross sectional study was conducted from February 2012-November 2012 among HIV-infected patients aged >18years attending the ART clinic of the UOG hospital. A pre-tested questionnaire was used to collect socio-demographic and clinical data. Sputum samples were collected for direct AFB microscopy and Mycobacteria culture. A PCR based RD9 deletion typing and genus typing was performed from all culture positive AFB isolates and drug-susceptibility testing was done for first line anti-TB drugs keeping SOP?s. Statistical analysis was performed using SPSS Version 20.0 software packages. Results: Our results showed that out of 250 HIV-infected participants, screened for TB through active case finding, 9(3.6%) were smear +ve /culture +ve and 6(2.4%) were smear -ve /culture +ve. RD9 typing showed that out of 15 isolates 10(66.6%) were M. tuberculosis species, 1(6.7%) belonged to Mycobacterium genus and four isolates were non Mycobacteria. Therefore, a total of 11 undiagnosed pulmonary TB infections were identified. All isolates were sensitive to RIF, INH and EMB. Mono-drug resistance was identified only for STM in one newly diagnosed TB patient and MDR-TB was not observed. Conclusion and Recommendation: The prevalence of undiagnosed PTB infection among HIV-infected patients in Gondar was 4.4%. Active screening of known HIV-infected individuals for TB, with at least one TB symptom should be considered.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords