Journal of Chromatography & Separation Techniques
Open Access

Adipose tissue and adipokines as promising therapeutic targets for obesity-associated cardiovascular and metabolic diseases

4^th World Congress on MASS SPECTROMETRY

June 19-21, 2017 London, UK

Yu Wang

The University of Hong Kong, China

Scientific Tracks Abstracts: J Chromatogr Sep Tech

Abstract :

Obesity is the major driving force for cardiovascular and metabolic diseases, the leading causes of mortality and morbidity in the aged population. Currently, 2.1 billion people ��? over 30% of the world��?s population ��? are either obese or overweight. This lifestylerelated epidemic has become and will continue to be a major societal, medical and economic problem in established and emerging industrialized countries. Adipose tissue (fat) is the largest energy storage and endocrine organ in the body. Adipose tissue dysfunction is the major culprit for obesity-associated cardiovascular and metabolic syndrome and has emerged as a promising therapeutic target. Here, I will summarize our discoveries during the past 15 years of proteomics-based research on a number of adipokines, including adiponectin, lipocalin-2 and adipocyte fatty acid binding protein (AFABP). In particular, I will demonstrate how the proteomicsbased bio-discoveries allow us to proceed with various therapeutic development based on the druggable domains/structures of these adipokines.

Biography :

Yu Wang has completed PhD at 2003 from University of Auckland, New Zealand. She has published more than 150 papers with high citations (H-index 42) and is serving as an editorial board member of various international reputed journals.

Email: yuwanghk@hku.hk