alexa Amphora Vaginal Gel: An On-demand Contraceptive With Anti-STI (MPT) Potential
ISSN: 2161-038X

Reproductive System & Sexual Disorders: Current Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

2nd International Conference on Reproductive Health
December 01-02, 2016 San Antonio, USA

David Robert Friend
Evofem Biosciences Inc., USA
Keynote: Reprod Syst Sex Disord
DOI: 10.4172/2161-038X.C1.001
Abstract
Amphora® vaginal gel is being developed as an on-demand, contraceptive vaginal gel. Moreover, Amphora has antimicrobial properties and its potential to protect women against some genital infections is being investigated. Amphora was evaluated as a vaginal contraceptive, compared to the commercially available spermicidal gel Conceptrol®, whose activity is derived from the surfactant nonoxynol-9. In addition, studies to investigate the anti-microbial activity of Amphora both in vitro and in animal models (especially the mouse vaginal challenge model) have been conducted. The phase three contraceptive efficacy clinical trial demonstrated that Amphora was non-inferior as a contraceptive compared with Conceptrol. The study confirmed that Amphora gel was non-inferior to Conceptrol under both perfect and typical use participants. There were no serious side-effects with either product. Amphora inactivated all seven gonococcal strains tested in vitro, and in the mouse vaginal challenge model only 1 out of 17 mice pre-treated with Amphora were infected, as compared to 13 out of 15 untreated mice. In similar studies with chlamydia, 3 of 16 mice pre-treated with Amphora were infected, compared to 14 of 16 given placebo. The same model was used in testing Amphora’s ability to protect against vaginal infection with the genital herpes virus (HSV- 2); of 26 animals pre-treated with Amphora, five were infected, compared to 22 out of 25 given placebo gel. If the promising antimicrobial findings translate into protection for women in the form, Amphora would be an important multipurpose prevention technology (MPT).
Biography

David Robert Friend has completed his PhD in Chemistry at University of California, Berkeley. He is the Senior Vice President of Research and Development and Technical Operations at Evofem Biosciences. He has published more than 100 research articles and reviews many on Female Reproductive Health including STI Prevention.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords