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Anal Melanoma: A Rare, But Catastrophic Tumor | 46819
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

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Anal melanoma: A rare, but catastrophic tumor

Global Summit on Melanoma & Carcinoma

Jose Antonio

Colorectal Division of Hospital Naval MarcĂ­lio Dias, Brazil

Posters & Accepted Abstracts: J Cancer Sci Ther

DOI: 10.4172/1948-5956.C1.073

Abstract
Introduction: Malignant melanoma of the anal canal is a rare and aggressive disease, whose early diagnosis is difficult. Its presentation with no specific symptoms leads to a late diagnosis at an advanced stage. The prognosis of anorectal malignant melanoma is poor and frequent related to distant metastasis and the absence of response of chemoradiotherapy. Surgery remains the mainstay of therapy; otherwise the best approach is controversial. Considering no survival benefits for APR, wide local excision should be considered as the treatment of choice. Methods: This report collects nine cases of anorectal melanoma treated at our division from June 1977 to 2006, as well as a review of the literature. Results: There were eight females and one male, of medium age 69 years (range: 41-85 years). Most frequent presentation was bleeding, with two of them with amelanotic melanomas. Wide Local Excision (WLE) was performed in seven of them. Mean survival was 24 months. Conclusion: Anorectal melanoma remains challenging. Efforts should be taken to early diagnosis, and wide local excision with negative margins is the preferred treatment. Abdominoperineal resection (APR) is a reasonable option for bulky tumors or when the sphincter is invaded.
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