This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Results of injection of autologous bone marrow mesenchymal stem cells (MSC) with
transfected GFP gene into the rat uterine horn cicatrix were studied by light microscopy.
Large groups of blood vessels with blood cells inside were seen after injection of MSC into
the cicatrix on the right horn, formed 2 months after its ligation; no groups of vessels of this
kind were found in the cicatrix in the contralateral horn. Examination of unstained sections
in reflected UV light showed sufficiently bright fluorescence in the endothelium and outer
vascular membrane in the uterine horn cicatrix only on the side of injection. Hence, after
introduction into uterine scar of MSC the increase of number of vessels due to the processes of
neoangiogenesis was detected. In this case the MSC do not migrate and were not destroyed in
the site of introduction, but formed the blood vessels due to differentiation into endotheliocytes
and pericytes. In 1 week in rats after introduction of MSC the vessels formed from these cells are
already fully functional, consist of all the structural walls and contain blood cells. The expression
of GFP gene not only in the vascular endothelium, but also in vascular outer membranes
indicated that autologous mesenchymal stem cells differentiated in the endothelial and pericytic
Igor V. Mayborodin, Date of Birth: November 19, 1962. 1991 - Defended a thesis for Ph.D. degree in Medical Sciences. 1998 - Defended a thesis for D.Sc.
degree (highest scientific degree in Russia) in Medical Sciences. 2000 - Assignment of an academic status of the Professor (Human Anatomy). He is the
Leading Research Scientist, Laboratory of Stem Cell, Institute of Chemical Biology and Fundamental Medicine. He has published more than 100 papers
in reputed journals and serving as an editorial board member of journal ?Surgical Science?
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals