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Anterior segment optical coherence tomography (ASOCT) is a new imaging modality
that uses low coherence interferometry to obtain
cross-sectional images of the
anterior segment of the eye in one image frame. ASOCT allows an objective assessment of
anterior segment structures. It is a non-contact optical system, can be performed under
standardized dark conditions, and can be operated with minimal expertise by a technician.
The anterior chamber angle can be evaluated using ASOCT even in the presence of a corneal
opacity. Hence, it may have potential for use as a screening tool to detect individuals at risk
of angle closure. Studies comparing ASOCT with gonioscopy found that ASOCT detected
more closed angles than gonioscopy, which is vulnerable to artefactual findings and
overestimation of the angle width. Furthermore, customized softwares now allow semi-
automated measurements of the anterior chamber parameters. Quantitative assessment of the changes in the anterior chamber
angle can be performed using ASOCT to evaluate the efficacy of treatments for angle closure. Recent applications of ASOCT
imaging include the assessment of trabeculectomy blebs and glaucoma drainage implants. There is significant potential for the
use of ASOCT in the rapid diagnosis of angle closure and in measuring the effectiveness of treatments. Integration of ASOCT
into clinical practice will help to refine and shape our management of glaucoma.
Dr Chelvin Sng graduated from Gonville and Caius College in Cambridge University with First Class Honours, and distinctions in
and Obstetrics and Gynecology. For her academic achievements, she was the elected senior scholar at Gonville and Caius College
(2001), and also
received the Max A. Barrett Prize (2002), William Harvey Studentship (2002-2004)and the Charles and Iris Brook Prize (2004). Af
she was awarded the Singhealth House Of
cer Award (2006), the International Travel Grant from the Association for Research in Vision and
Ophthalmology (2008), and the Australian and NewZealand Glaucoma Interest Group Scholarship (2010).
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