alexa Antibody-directed Cellularization Of Heart Valve Implants
ISSN: 2157-7552

Journal of Tissue Science & Engineering
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

2nd International Conference on Tissue Science & Regenerative Medicine
August 26-28, 2013 DoubleTree by Hilton, Raleigh, NC, USA

J. Koudy Williams
Symposium: J Tissue Sci Eng
DOI: 10.4172/2157-7552.S1.010
Abstract
O ur goal is to develop and test a bioengineered heart valve for pre-clinical testing and eventualtranslation into clinical use. Initial efforts were to develop heart valve implants pre-seeded with autologous endothelial cells and then conditioned in a bioreactor prior to insertion. Simultaneously, we developed a column (containing speharose beads conjugated with CD133mAb that could collect endothelial precursor cells (EPCs) efficiently from the blood stream when placed as anarterio-venous shunt. Using this same basic approach Dr. Williams assumed and conjugated CDE133mAb on to heart valve scaffolds - process that took 2 hours - and implanted them in the pulmonary position of sheep. The result showed that antibody conjugation accelerated receullularization and structural maturation of the implants and provided preliminary data that these valves may remodel and grow with the patient
Biography
J. Koudy Williams is currently a Professor at the Wake Forest Institute for Regenerative Medicine (WFIRM). He spent his first 17 years at Wake Forest in The Department of Pathology/Section on Comparative Medicine exploring the effects of oral contraceptives and hormone replacement therapy on coronary heart disease risk in the coronary arteries of atherosclerotic monkeys. Eight years ago, he joined WFIRM and has since focused his research on regenerative medicine approaches for organ repair and replacement
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version