alexa Anti-inflammatory Activity Of Lavandula Antineae Maire From Algeria
ISSN: 2167-0501

Biochemistry & Pharmacology: Open Access
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9th World Congress on Pharmacology
September 04-06, 2017 | Paris, France

Soumeya Krimat and Aicha Kesouri
ENS, Kouba, Algeria
Posters & Accepted Abstracts: Biochem Pharmacol (Los Angel)
DOI: 10.4172/2167-0501-C1-007
Abstract
Lavandula antineae Maire is an endemic medicinal plant of Algeria which is traditionally used as a popular remedy against chills, bruises, edema and rheumatism1. The objective of this study is to evaluate the anti-inflammatory activity of the hydromethanolic extract of the aerial parts of Lavandula antineae for the first time using two models of inflammation: carrageenan-induced paw edema and ear edema induced by croton oil 2,3. In the first model, the pretreatment of mice, by the plant extract, inhibited significantly the development of edema in a dose-dependent manner, with kinetics of action similar to that of aspirin (reference product) . In addition, the local application of 2 mg of extract induced a very significant reduction (P<0.05) of ear edema compared to the control group with a inhibition of 74.67 %. These results demonstrate that the Lavandula antineae Maire species has an important anti-inflammatory activity, thus justifying its folkloric use as a remedy for various inflammatory disorders.
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