alexa Aptamers And Bio-sensing
ISSN: 2155-6210

Journal of Biosensors & Bioelectronics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
In Association with
 
romanian
 
icamb2015

7th Euro Biosensors and Bioelectronics Conference
July 10-11, 2017 Berlin, Germany

Shalen Kumar
AuramerBio Limited, New Zealand
Victoria University of Wellington, New Zealand
Posters & Accepted Abstracts: J Biosens Bioelectron
DOI: 10.4172/2155-6210-C1-034
Abstract
Synthetically derived single-stranded nucleic acid species, also known as aptamers, have been generated under in vitro conditions using a sequential enrichment and mutational approach referred to as systemic evolution of ligands by exponential enrichment (SELEX). Aptamers generated in this way have been shown to bind a variety of targets such as organic and in-organic molecules in addition to larger molecules such as proteins. Aptamers are now being used in a variety of medical and bio-sensing applications. However, despite significant advances in the bio-sensing platforms, the generation of highly sensitive and specific aptamers capable of binding small molecular weight compounds is still limited. Aptamers to small molecular targets were selected from a random library of nucleotide sequences using SELEX. The resulting aptamers are sequenced and binding affinities are characterized (binding affinity constants Kd) prior to application on sensing platforms. In addition, structural differences between an aptamer and its ligand give rise to the formation of a unique complex where a specific region of the aptamer is involved in binding to the ligand (known as the ligand binding domain, LBD). Utilization of the parent aptamer (e.g., 75mer) or the LBD-aptamer region (e.g., 38mer) influence the limit of detection (LOD) achieved when using platforms such as a gold nanoparticle (AuNP) or electron impedance spectroscopy (EIS) based system.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords