alexa Assesment The Effect Of Corticosteroid Therapy On Alveolar Surfactant Development In Risk Newborn Children By Novel Biophysical Methods | 72803
ISSN: 2165-7920

Journal of Clinical Case Reports
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

5th European Conference on Clinical and Medical Case Reports

Vishnya Stoyanova, Bangyozova, Asya Tsanova1, Albena Jordanova, Detelina Petrova, Emilia Christova and Zdravko Lalchev
Ohridski University of Sofia, Bulgaria
Multiprofile Hospital for Active Treatment, Bulgaria
Medical University of Sofia, Bulgaria
Posters & Accepted Abstracts: J Clin Case Rep
DOI: 10.4172/2165-7920-C1-012
The relative percentage of risk newborn children in Bulgaria increases progressively and in 2015 reaches 11.4%. Neonatal respiratory distress syndrome (NRDS) is a leading cause for up to 30 % of prematurely newborns mortality in our country. The aim of the present study was to apply novel methods for early, fast and noninvasive diagnostics of lung maturity in risk newborns, which would contribute for the choice of correct strategy for lifesaving surfactant therapy. For this purpose by pendant drop method by axisymmetric drop shape analysis (ADSA) and Brewster angle microscopy (BAM) gastric aspirates (GA) from risk newborn children were studied. GA were taken from prematurely born with primary surfactant deficiency, infants born after in vitro fertilization, after corticosteroid therapy of the pregnant female, and control group of healthy full term infants. Our analyses showed higher values of minimum surface tension of the GA taken from NRDS children, as compared to the control group, showing immature alveolar surfactant. This parameter was improved after corticosteroid therapy. In addition, BAM images confirmed the results from ADSA: The monolayers of GA from NRDS children were loose and thin in contrast to those from the control group. After corticosteroid therapy, the monolayers were with better characteristics. Our data proved that the corticosteroid therapy applied 24 hours before delivery resulted in enhanced development and secretion of alveolar surfactant in preterm babies.

Vishnya Stoyanova has completed her PhD from Faculty of Biology, Sofia University. She is a Chief Assistent Professor in Biochemistry and Faculty in Medicine, Sofia University. She has published 15 papers in reputed journals.

image PDF   |   image HTML

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037


James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

generalscience[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals


Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T


[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version