alexa Assessing The Role Of Prostate-specific Antigen In Screening And Diagnosis Of Prostate Cancer
ISSN: 1948-5956

Journal of Cancer Science & Therapy
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3rd World Congress on Cancer Science & Therapy
October 21-23, 2013 DoubleTree by Hilton Hotel San Francisco Airport, CA, USA

Radul Olga V, Chernomorez Dasha V and Lysenko Victoria V
Posters: J Cancer Sci Ther
DOI: 10.4172/1948-5956.S1.029
Introduction:The current and important task of screening is the selection of patients for transrectal polyfokal prostate biopsy (TRPPB) controlled transrectal ultrasound, which is based on data prostate-specific antigen (PSA), digital rectal examination data and transrectal ultrasound (TRUS). Purpose: is a determination of specificity, accuracy, and reliability of PSA for the diagnosis of prostate cancer (PC), depending on its absolute value. Materials and methods: An analysis and a study of 316 patients? diagnostic data from 2006 to 2010, which carried out by TRPPB and controlled by TRUS within 10-14 points. Analysis and results: If PSA levels of 0-4 ng/ml, then the benign processes in the prostate (BPP) were found in 80% of patients, while the PC is detected in 20% of cases. If PSA levels are 4-10 ng/ml, then BPP is in 55.7% of patients, and PC is in 44.3% of patients. If PSA levels are 10-20 ng/ml, then BPP is in 47.2% of patients, and PC is in 52.7% of patients. If PSA level is 20 ng / ml or more, then BPP is in 12.3% of patients, and PC is in 87.7% of patients. There is a high significant difference (p <0,001, t> 2,0) in the frequency of detection of PC in marker levels between 20 ng/ml and more. If the PSA level at 0-4 ng/ml, then the specificity this marker is 20%; if PSA level at 4-20 ng/ml, then the specificity is at 52%; and if a PSA level at 20 ng/ml and more, then the specificity is at 88%. There is a relationship between age men and frequency of PC. The observed satisfactory reliability of differences (p <0,05, 0,0
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