alexa Assessment Of The Gastropanel Test As A Non-invasive Diagnosis Of Atrophic Gastritis
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

3rd World Congress on Cancer Science & Therapy
October 21-23, 2013 DoubleTree by Hilton Hotel San Francisco Airport, CA, USA

Alonge Ivo Ebule
University of Yaounde I, Cameroon
Accepted Abstracts: J Cancer Sci Ther
DOI: 10.4172/1948-5956.S1.030
Abstract
G astric colonization by Helicobacter pylori increases the risk of atrophic gastritis and gastric cancer. Serum levels of pepsinogen I and gastrin-17 which are respectively biomarkers of corpus and antrum mucosal activity are well known parameters of atrophic gastritis. We examined the diagnostic efficacy of GastroPanel serological kit (pepsinogen I& II, gastrin-17 and H. pylori IgG), in diagnosing and scoring atrophic gastritis. Dyspepsia patients undergoing gastroscopy with biopsy were recruited prospectively on voluntary basis at the Yaounde Central and University Teaching Hospitals, from March to July 2011. The degree of atrophy was classified according to levels of serum pepsinogen I &II, gastrin-17 and H.pylori IgG and compared with histological profiles. 86 volunteers aged 21 to 83, mean ± C.I. (46.4±3.3) were enrolled. The prevalence of gastritis was statistically similar between GastroPanel test and histology (89.5% versus 83.7%: p>0.20). However, the GastroPanel diagnosed more atrophic gastritis than histology (17.4% versus 7.0%: p<0.01), especially at antrum of stomach with H. pylori infection. For the scoring of atrophy, the accuracy (69.77%), sensitivity (85.70%) and specificity (88.60%) were calculated. The prevalence of H. pylori-infection did not differ significantly between serological and histological methods (84.9% versus 81.4%, p>0.05). These results suggest that diagnosis of atrophic gastritis and H. pylori infection obtained with an optional serological method, GastroPanel is in strong agreement with biopsy findings, and thus can be a useful non-endoscopic assessment of stomach mucosal atrophy in patients with dyspepsia.
Biography

Alonge Ivo Ebule has completed his M.Sc. in Medical Immunology at the age of 30 from University of Yaounde 1 in 2012 and a Bachelor of Medical Laboratory Sciences from the University of Buea in 2007. Since 2006, he has assumed a leadership role in gastric research. He is a consultant with the Ministry of Public Health and several non-governmental organizations. He has published 03 papers in gastric diseases and has participated actively in other research areas including immunopathology of malaria and onchocerciasis with the use of cytokines along the Sanaga valley of Cameroon.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords