alexa Autism Spectrum Disorder From Valproic Acid | 64438
ISSN: 2329-6895

Journal of Neurological Disorders
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

International Conference on Neurological Disorders & Stroke and Neurooncology
April 24-25, 2017 Dubai, UAE

Sharmila Alam
University of Calgary, Canada
ScientificTracks Abstracts: J Neurol Disord
DOI: 10.4172/2329-6895-C1-017
Abstract
Introduction: Autism spectrum disorder (ASD) is a behaviorally defined brain disorder affecting approximately 1 in 150 children. Autistic children exhibit impoverished verbal and non-verbal communication skills and reduced social interactions. Several studies have shown that in utero VPA (valproic acid) exposure may link to an increased risk of ASD, where, for example, it has been reported that the rate of ASD in the children of VPA-treated mothers may be roughly eight times larger than that of the general population. The purpose of the study is to observe whether VPA can influence the speed of postnatal maturation in vivo and whether this can be associated with structural and behavioral characteristics related to autism. Methodology: Although the effects of VPA have been tested in rodents for many years, only relatively recently it has been used to model ASD in rodents for studying ASD-like behavioural features such as social play behaviors. Findings: We found that VPA treated animals can exhibit gross cortical hypertrophy and a reduced predisposition for social play behavior. Conclusion & Significance: Structural and behavioral findings from this research suggests that alteration of the developmental time course in certain high-order cortical networks may play an important role in the neurophysiological basis of autism.
Biography

Sharmila Alam is a Neuroscience Researcher from 2006 to 2010 in University of Calgary, Canda. She obtained MSc in Biochemical Engineering from the same university. During her research, she worked with animal models (rat and mice) with neurological diseases to look for potential treatments. She has several publications in different journals. Her inquisitiveness to find out the hidden mechanism, hope to find a cause and cure that can improve the quality of life of millions of people and her passion for science keeps her going.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version