oncerns have been raised that the amphibian larval stages are particularly at risk and may be vulnerable to adverse effects of
pesticides. The present study reports acute toxicity of cypermethrin at 24, 48, 72 and 96 h through static renewal bioassay
. The LC
values were 5.15, 4.55, 3.95, and 3.34μg/L for 24, 48, 72, and 96 h respectively.
At sublethal concentration (0.33μg/L) behavioral, morphological and biochemical changes were studied. The behavioral and
morphological anomalies observed in the present study are typical signs of cyano pyrethroid poisoning. Significant changes
were observed in total, soluble, and structural proteins. The depletion of all the protein fractions observed in this investigation
led to progressive protein oxidation and catabolism of proteins. Decreased protein level has resulted in a marked elevation of
free amino acid levels at all time intervals. The induction of catalase, glutathione-S-transferase activities and elevation in the
levels of hydrogen peroxide, reduced glutathione, and malondialdehyde eventually lead to oxidative damage of biomolecules,
showing that the generation of reactive oxygen species and oxidative stress are involved in the toxicity induced by cypermethrin.
Indicating increased susceptibility of tadpoles. Thus, an exposure to cypermethrin at sublethal concentration had catastrophic
effect on tadpoles of
Muniswamy David completed his education (M.Sc., M.Ed., M.Phil., Ph. D.) at Andhra Pradesh, India. After short service in State Fisheries Department
at Andhra Pradesh, later he entered teaching profession at Karnatak University, Dharwad, Karnataka, India. Dr. David significantly contributed in
the field of aquatic toxicology, Ecotoxicology and fishery biology. He is the member of editorial board for many peer reviewed research journals. He
published more than 70 research papers in peer reviewed national and international journals. He is guiding many research scholars for their Ph.D.
and M.Phil degrees and he is handling many funded research projects
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