alexa Biodegradable Poly[(d,l)-lactide-co-glycolide] Nanofibrous Membranes Providing Sustainable Release Of Carmustine In The Cerebral Cavity | 9387
ISSN: 0974-7230

Journal of Computer Science & Systems Biology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

International Conference on Integrative Biology Summit

Dave Wei-Chih Chen, Jun-Yi Liao and Shih-Jung Liu
Accepted Abstracts: J Comput Sci Syst Biol
DOI: 10.4172/0974-7230.S1.004
Abstract
In this study, we developed biodegradable poly[(d,l)-lactide-co-glycolide] nanofibrous membranes via electrospinning that provided a sustained release of BCNU. An elution method and a HPLC assay were employed to characterize the in-vitro and in-vivo release behaviors of pharmaceuticals from the electrospun membranes. The experimental results show that the biodegradable, nanofibrous membranes released high concentrations of BCNU for more than 6 weeks in the cerebral cavity of rats. Furthermore, the membranes can better conform to the geometry of the brain tissue and can cover more completely the tissue after the removal of tumors, achieving better drug transport without interfering with the normal function of the brain. Histological examination showed no obvious inflammation reactions of the brain tissues. By adopting the electrospinning technique, we will be able to manufacture biodegradable, nanofibrous membranes for the long-term deliveries of various anti- cancer drugs in the cerebral cavity, which can enhance the therapeutic efficacy of GBM treatment.
Biography
S.J. Liu earned his Master and Ph.D. degrees from Cornell University and the University of Wisconsin at Madison in 1989 and 199 2 respectively. Prof. Liu had been working as a Post-doctoral research fellow at McMaster University of Canada, and also been as a visiting professor to the Tokyo Institute of Technology in Japan and Aachen University of Applied Science in Germany. Prof. Liu received the Morand Lambla Award from the International Polymer Processing Society in 2008. He is the author of more than 200 scientific publications including 120 referred journal papers, editor and co-editor of 6 books and the author of 15 patents. Prof. Liu is also serving as the Editor of Journal of Polymer Engineering (SCI) and the Associate Editor of Asia Pacific Journal of Chemical Engineering (SCI).
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

kactakapaniyor.com

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

Taktube

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

sikiş

[email protected]

1-702-714-7001Extn: 9037

instafollowers

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

putlockers

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

seks

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version