alexa Biologic Systemic Therapy For Moderate To-severe Psoriasis: Emphasis On Quality Of Life | 68485
ISSN: 2167-0870

Journal of Clinical Trials
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

8th Global Pharmacovigilance & Drug Safety Summit

Ali A Mustafa
King Fahd Medical City, KSA
Posters & Accepted Abstracts: J Clin Trial
DOI: 10.4172/2167-0870-C1-017
Abstract
Statement of the Problem: Psoriasis is one of the autoimmune diseases of particular interest. It is a chronic, relapsing and remitting inflammatory skin and joint disease that has a prevalence of 2-3% worldwide. Ethnic variations have been identified and Caucasians are more likely to suffer from the disease. Chronic plaque psoriasis is a lifelong disease with a substantial impact on the physical well-being and quality of a patient's life. As with all autoimmune diseases, the pathophysiology of psoriasis is complicated and not yet fully understood. However, the signs and symptoms appear to be caused by hyper proliferation and inflammation of epidermal cells. In psoriasis, an immunologic response involving T-lymphocytes and cytokines alters the epidermal skin cell cycle resulting in psoriatic plaques. Like other autoimmune diseases a mixture of genetic, environmental and behavioral influences are involved and or are associated with its development. Methodology & Theoretical Orientation: Randomized double-blind, placebo controlled studies have reviewed using the data basis of Cochrane, Embase and PubMed. 4 biologic therapies (adalimumab, efalizumab, Etanercept and infliximab) which had been thoroughly revised are now licensed for the treatment of moderate-to-severe psoriasis. Conclusion & Significance: Randomized double-blind, placebo controlled studies have demonstrated the short-term efficacy and safety of all therapies for psoriasis. However, these data may not reflect practical day-to-day experience. Patients who need such biologics are those who are suffering from the most severe forms of psoriasis. However, combinations of traditional systemic and biologic therapies may be required. Treatments are time consuming and ineffective, and patients experience side effect as the most negative aspect of current treatments. Recommendations are made for treatment is also reflected in the Quality of Life research. Also, there is ample evidence that psoriasis can have a profound effect on patients’ functioning and wellbeing.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7