This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Label-free immunoassay sector is a ferment of activity, experiencing rapid growth as new technologies come forward and achieve
acceptance. The challenges can be broken down into several key aspects as: sensibility and competitive limit of detection, ability
of measuring molecules with different molecular mass, low reagent consumptions and the capability of measuring with simple drops
for measuring different molecules simultaneously. The landscape is changing in a ?bottom up? approach, as individual companies and
research groups promoting key remarkable technologies. However, not many technologies based on Label-free technology are currently
in the market, where mature labeled technologies such as lateral flow for its simplicity and ELISA for its sensitivity as one of the most
employed techniques nowadays. Biophotonic Sensing Cells (BICELLs) defined as Bio-Sensitive cells that can be integrated in wells
and interrogated vertically by enhanced optical techniques is currently an interesting approach for measuring biological agents as a
label-free alternative for its capability of multiplexing many sensing sites in a single well, and therefore multiples diagnostics can be
implemented simultaneously. Furthermore, good figures of sensitivity have been demonstrated for measuring different biological agents
such as proteins, hormones and viruses, even in real samples. Several BICELLs type have been proposed and published. A good example
is that based on network of nanopillars made of low-cost resist, where bioreceptors can be immobilized easily. BICELLs technology is
an interesting technology to face the unmet need for reliable diagnostic tools that ensures sensitive, rapid and simple analysis through
a simple PoC reader.
Miguel Holgado received Ingeniero Industrial degree (1996) from Universidad Polit?cnica de Madrid (UPM), and Doctor Ingeniero Industrial degree
(Ph.D.) at the Spanish National Research Council from the same University (2000). He is currently Group Leader of the Micro-nano Photonics and
Biophotonics at the UPM Laser Centre and Associate Professor at the Applied Physics Department of ETSII (UPM). He has more than 4 years
experience working in R&D in Industrial Sectors and was a Spanish Representative in the 5th and 6th European R&D Framework Programme. He
is author/co-author of multiple publications in international journals cited more than 800 times.
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals