alexa Bone-like Nanocomposite Of Hydrxyapatite And Collagen As Artificial Bone
ISSN: 2169-0022

Journal of Material Sciences & Engineering
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

3rd International Conference and Exhibition on Materials Science & Engineering
October 06-08, 2014 Hilton San Antonio Airport, USA

Masanori Kikuchi
ScientificTracks Abstracts: J Material Sci Eng
DOI: 10.4172/2169-0022.S1.014
Bone is a typical nanocomposite mainly composed of carbonate containing non-stoichiometric hydroxyapatite nanocrystals and type-I collagen molecules. They aligned along each other in the primary structure of bone and realize strong but biologically resorbable nature. Our group hypothesized that artificial bone with similar chemical composition and nanostructure would be excellent materials for bone regeneration as the same as natural bone. Simultaneous titration of Ca(OH)2 and collagen- H3PO4 solutions under controlled reaction pH and temperature allows to synthesize bone-like nanostructured hydroxyapatite/ collagen nanocomposite (HAp/Col) very easily. The HAp/Col can be formed into dense and porous bodies, membrane and self-setting paste. The HAp/Col is incorporated into bone remodeling paste when it is implanted into bone defect. The porous body of the HAp/Col (HAp/Col sponge) showed sponge-like viscoelasticity in wet condition and fit to any shape of bone defect very easily. The HAp/Col sponge showed higher efficacy for regenerating small to large bone defect in comparison to bioderadable β-tricalcium phosphate porous body in human clinical trial, by its excellent bioactivity and fitting ability to bone defects. The HAp/Col sponge is already sold in Japan as Refit?. Recently, we found that the HAp/Col coating on Ti metal accelerate by 3 times to form direct bonding between host bone and Ti implant. In addition, paste for minimum invasive surgery as well as 3D printing and gene transfer substrate using the HAp/Col were investigated. Including these, possibility of the HAp/Col nanocomposite will be presented in the symposium.
Kikuchi has completed his PhD from Waseda University, Japan and postdoctoral studies from National Institute for Research in Inorganic Materials. He is the leader of Bioceramics group in National Institute for Materials Science as well as Professor of Hokkaido University. He has published more than 100 papers with h-index of 22 and serving as board member of several scientific societies and a convener of ISO / TC150.
image PDF   |   image HTML

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version