Mutual depending on one another intracellular balance catabolic and anabolic processes with extracellular balance
catabolic and anabolic processes promote maintenance stability Internal Medium (concentrations of substances in blood and
in neurolymph) and Internal Energy (temperature 36,5
C ? 37,2
C, by which all enzymes operate, etc.) of an organism and cells
in norm. Unlike norm, the excessive shift into anabolic endoergonic processes of intracellular balance catabolic and anabolic
processes suppress catabolic exoergonic processes which is characteristic cancer tissue metabolism in comparison with the
excessive shift into catabolic processes characteristic inflammatory processes.
It was offered the common concept of Warburg effect mechanism that was enabled to explain the mechanisms
of cancer manifestations as well as to eliminate the doubts and/or queries which were expressed by the authors of the some
experiments. Highlight: As outcome of oncogenes operation the huge anabolic processes cause huge consumption of
energy and Acetyl-CoA and suppress the catabolic processes in cancer tissue. Lactic acids accumulate energy for anabolic
processes in condition glycolisis metabolism in cancer tissue.
This concept gives possibility to explain Warburg effect mechanism and distinction between mechanisms
Pasteur effect and Warburg effect. Besides it gives possibility to explain mechanisms of unhealed cancer wound, irrepressible
cancer growth, metastasis etc. Also the violations mechanisms of maintenance stability Internal Medium and Internal Energy
of an organism by cancer disease development was elucidated in comparison with the violations mechanisms of maintenance
stability Internal Medium and Internal Energy of an organism by inflammatory processes. All of it gave possibility to eliminate a
lot of doubts and/or queries which were expressed by the authors of the some experiments.
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