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|Ghada Ismail, Sally M Saber and *Ahmed Elshafei|
|Ain Shams University, Egypt|
|ScientificTracks Abstracts: J Clin Case Rep|
|Background: Leuconostoc species are important pathogenic bacteria in individuals with poor immune function especially liver transplanted patients. Leuconostoc species are catalase-negative, gram-positive microorganisms with coccoid morphology which have been previously considered as agents that cause severe hospital outbreaks that threaten the lives of large numbers of persons. Objectives: To isolate& differentiate Leuconostoc species among Vancomycin Resistant Enterococci (VRE) isolates which recovered from clinical specimens of liver transplanted patients. Patients & Methods: Forty liver transplanted patients in Ain Shams University Specialized Hospital were involved in this study that had the criteria of post-operative biliary infection over a period of one year from January to December 2010.Liver function tests, Complete blood count, Doppler ultra-sonography on the abdomen and Magnetic Resonance.Nasal and biliary secretions were collected and submitted for culture and sensitivity. Twenty clinical isolates of Vancomycin Resistant streptococci were isolated from twenty patients (from both bile and nasal swabs). The strains were identified by conventional microbiological techniques; API20 Strept, sequencing PCR and antimicrobial susceptibility by disk diffusion method & Vancomycin E-test was done. Results: Two Leuconostoc paramesentroids isolates were identified among 20 clinical isolates of VRE. Both were isolated from one patient (nasal and bile) which were sensitive to Penicillin, Ampicillin, Erythromycin, Gentamycin, Teicoplanin, Tetracycline, Clindamycin and resistant to Vancomycin(MIC ≥256mg/mL). Conclusion: Leuconostoc species may be considered as a colonizer with potential pathogenicity especially in immuno-compromised transplanted patients which must be screened and differentiated from VRE isolates.|
Ghada Ismail is a Professor of Clinical & Chemical Pathology since 2008 at Faculty of Medicine , Ain Shams University and has completed MD degree in 1998. Director laboratories of Ain Shams University Specialized hospital, Secretary of Supreme Infection control Committee University hospitals, Board member of TQM Diploma, Open Education, Ain Shams University.
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