Serotonin has been involved in distinct physiological processes by the activation of their receptors subtypes. In this work we
studied the changes on the expression of 5-HT(5A) receptors in rat hippocampus induced by the chemical leptin which
has been involved in the modulation of food intake., We used the immunohistochemistry in order to know the changes in the
distribution for the 5-HT5A receptor in the hippocampus. Rats were separated in four groups: control (untreated rats), leptintreated,
serotonin-treated and leptin+serotonin treated. The results showed that treated rats with leptin and serotonin, the specific
immunostaining for the 5-HT(5A) serotonin receptor decreased significantly in the dentate gyrus.
Guadalupe Garc?a Alcocer completed her PHD from National University of Mexico. She is professor at the University Autonomous of Queretaro,
Mexico. She has published more than 15 papers, presented 25 works in International meetings and 30 in National meetings. She is serving as
referee in repute journals like Brain research and Neurscience Letters. She formed more than 35 students and is member of the National Research
System since 2005.
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