Natural Products Chemistry & Research

ISSN - 2329-6836

Chemical constituents of the leaves of Ficus nitida and their antimicrobial activity

3rd International Conference and Exhibition on Pharmacognosy, Phytochemistry & Natural Products

October 26-28, 2015 Hyderabad, India

Hassan Abdalla Almahy Dafalla1, 2

1Taif University, KSA 2University of Bahri, Sudan

Posters-Accepted Abstracts: Nat Prod Chem Res

Abstract :

The dichloromethane extract of the air-dried leaves of Ficus nitida belongs to the family Moraceae afforded lutein (1), β-sitosterol (2), stigmasterol (3), chlorophyll a (4), phytol (5), (E)-3-alkenoic acid (6), triglycerides, fatty alcohols and fatty acids while the twigs yielded saturated fatty acid ester. The structures of 1-5 on the basis of spectroscopic data such as IR, UV, 1H-NMR, 13C-NMR, COSY, HMQC, HMBC, DEPT and MS and confirmed by comparison data with those reported in the literature. The structure of 6 was elucidated by 1D and 2D NMR spectroscopy. However, bioactivity screening showed that the pure isolated compounds possessed activity on two species of bacteria Bacillus cereus NRRLUI-1447 and Pseudomonas aeruginosa UI-60690 and no activity against four species of fungi (Aspergillus ochraceus NRRL 398, Candida lipolytica ATCC 2075, Sacchromyces cereviseae NRRL 2034 and Sacchromyces lipolytica).

Biography :

Hassan Abdalla Almahy Dafalla has completed his PhD from University Putra Malaysia. Currently he is a Professor at the Department of Chemistry from Taif University Saudi Arabia.

Email: abuamna4@hotmail.com

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