alexa Comparison Of Anxiolytic Effects Of The Homeopathic Complex Vita-C 15 When Compared To Aconitum Napellus In The Acutely Stressed C57BL6 Mice
ISSN: 2327-5162

Alternative & Integrative Medicine
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7th International Conference on Ayurveda, Homeopathy and Chinese Medicine
May 18-19, 2017 Munich, Germany

Siaw Min Liew
Cyberjaya University College of Medical Sciences, Malaysia
Posters & Accepted Abstracts: Altern Integr Med
DOI: 10.4172/2327-5162-C1-024
Abstract
Anxiety, phobias and stress are the main mental health problems among the Malaysian population, with global prevalence varying from 8% to 18%. Even so, less than 30% who suffer from these disturbances seek treatment. The objective of this study was to evaluate and compare the anxiolytic effects of Aconitum napellus and Homeopathic complex vita-C 15 in the acutely stressed C57BL6 mice by using the faecal corticoid test, open field test (OFT) and c-fos, NMDAR 2B, NPY 1R and NPY 2R activity through the hippocampus. A double blinded randomized controlled study is conducted at Animal Laboratory of Cyberjaya University College of Medical Sciences (CUCMS). All the animals are acclimatized to constant laboratory conditions for 14 days before starting the experiments. Prior to the experiment, a pilot study was performed to identify the most suitable and ideal potency for the homeopathic remedy of Aconitum napellus. The animals are tested (n=3) per group on the potency of 6 C, 30 C and 200 C. The treatments are carried out over 9 days. 48 male C57BL6 mice (n=6), 4-5 weeks of age are used. They are randomly selected and divided into two groups. Group I is the healthy control group of mice which are not exposed to acute stress. Group II (stress group); comprises of mice exposed to acute restraint stress. Prior to restraint stress, the treatments given are Aconitum napellus 30 cH, Homeopathic complex Vita-C 15, Diazepam, and placebo. Then the results are evaluated by faecal CORT test and open field test by comparing the anxiolytics between pre-test and post-test. Aconitum napellus 30 cH and Homeopathic complex vita-C 15 are expected to be more effective and can reduce the occurrence of anxiety in the acutely stressed C57BL6 mice. Thus, research into prevention and supportive therapies is necessary and beneficial for this disorder.
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