alexa Current Mumps Outbreak In Belgium: Is Laboratory Confirmation By IgM Useful?
ISSN: 1948-5964

Journal of Antivirals & Antiretrovirals
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

4th World Congress on Virology
October 06-08, 2014 Hilton San Antonio Airport, TX, USA

Seaux L
Accepted Abstracts: J Antivir Antiretrovir
DOI: 10.4172/1948-5964.S1.022
Nonetheless the vaccination status of the Belgian population is high, we are currently facing an outbreak of mumps. This current outbreak started in March 2012 among Ghent university students. The genotype G variant, not endemic to our regions, was the culprit. Fully immunised patients were infected because current vaccins only contain mumps genotype A antigens as well as currently available laboratory tests. The aim of this study was to evaluate the influence of currently circulating genotype G on the performance of routine mumps IgM test (Enzygnost? Anti-Parotis-Virus/IgM, Behring Elisa Processor III, Siemens) at the Ghent University Hospital. Based on laboratory information system query for March 2012 till March 2013, only patients with a serological request form consistent with the possible clinical picture of mumps were included. Secondly, the electronic patient records of all withhold cases were carefully examined. From 395 analysed cases, 92 presented with a suspicious clinical picture for mumps. Sixty patients (65%) were between 14 and 28 years old. In 57 out of 92 patients (62%) mumps was actually clinically diagnosed. Only 24 of these 57 clinically clear cases (42%) showed positive mumps IgM. In total 29 of 92 cases (31.5%) tested mumps IgM positive. It is reported in the literature that time between the onset of symptoms and IgM positivity is crucial. The critical point is 2 days after the start of the symptoms: before that point the positivity of PCR is rather expected. In the group of clinically clear cases the onset of symptoms was reported for 31 from 54 (57%) patients. Twelve patients from this group had a positive IgM result. The onset of symptoms was more than 2 days in 91% (11/12) of the cases. Nineteen clinical cases had a negative IgM result, of these group 68% (13/19) of the patients had less than 2 days symptoms. In conclusion, in the current outbreak the routine IgM mumps test was not fitted to confirm the clinical diagnosis. The positivity rates were as expected higher if the symptoms were present for more than 2 days. Our study emphasizes that mumps diagnosis should be made on clinical basis.
image PDF   |   image HTML
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version