alexa
Reach Us +1-504-608-2390
Cytokines Pattern Of Multiple Sclerosis Patients Treated With Apitherapy | 36068
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Cytokines pattern of multiple sclerosis patients treated with Apitherapy

4th International Conference and Exhibition on Immunology

Ahmed G Hegazi, Khaled Al-Menabbawy, Eman H Abdel-Rahman and Suzette I Helal

National Research Center, Egypt

ScientificTracks Abstracts: J Clin Cell Immunol

DOI: 10.4172/2155-9899.C1.024

Abstract
Objective: Examined cytokines in serum samples from 80 patients with multiple sclerosis treated with apitherapy in particular using bee sting therapy. Methods: Eighty patients with MS, their ages ranged between 26-71 years, were subjected to complete clinical and neurological history and examination to confirm the diagnosis. All cases were under their regular treatment they were divided into two main groups, Group I received honey, pollen, royal jelly and propolis and were treated with apiacupuncture 3 times weekly, for 12 months, in addition to their medical treatment, while group II remains on their ordinary medical treatment only. IFN-γ, interleukin (IL) 1β, IL-4, IL-6, IL-10, tumor necrosis factor alpha (TNFα) were detected. Apiacupuncture was done by bee stings for regulating the immune system. Results: Results revealed that 12 patients showed some improvement regarding their defects in gait, bowel control, constipation and urination, while 28 cases, showed some mild improvement in their movement in bed, and better improvement in bed sores, sensation, and better motor power, only six cases of them were able to stand for few minutes with support. The level of IFN-γ, (IL) 1β, IL-4, IL-10, TNF-α was significantly elevated in patients in Group II, and no significant differences were found for IL-6 between the 2 groups of treatment. The mean values of IgE level in both groups of M.S. patients were low but with no statistical significance, while by the end of the study there were an elevation in the levels of IgE for both groups which was statistically significant. Conclusion: Although Apitherapy is not a curable therapy in MS, but it can be used to minimize the clinical symptoms of MS and evaluating responses to specific therapies which can be included among programs of MS therapy. Cytokines in multiple sclerosis may help to identify mechanisms involved in the pathogenesis of the disease.
Biography

Ahmed G Hegaziworked as a Professor of Microbiology & Immunology, National Research Center, Dept. Parasitology, 1997-2000, Chair of Faculty of Medicine, Zagazig University, 1981-1997, part-time Professor and Supervisor of Immunology Section, National Research Center, 1990- up till now. He is also Prof. of Microbiology & Immunology, African Federation of Apiculture Associations (AFAA), 2001- up till now, Standing Commission on Apitherapy (APIMONDIA), 1999 - up till now, Member of Standing Scientific Committee, National Research Center, 1998 –up till now. He was awarded the Excellent Medal of the First Class, 1995, received the Senior Scientist Prize of National Research Center, 1996, and won The Second Best Research Paper award from International Congress of Propolis, Argentina, 2000. He has published in Egyptian Journal of Immunology, 1995, was in the Editorial Board of The Egyptian Association of Immunologists, 1992 –1997, Secretary General, Referee in 37 international journals patents: 4 Patents Educational Activities. He has published 193 articles in national and international scientific journals, 6 books in English and 7 books in Arabic.

Email: [email protected] [email protected]

Top