alexa Cytotoxic Activity Of Acyl Phloroglucinols Isolated From The Juvenile Leaves Of Eucalyptus Cinerea F. Muell. Ex Benth. Cultivated In Egypt | 15927
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

3rd World Congress on Cancer Science & Therapy

Maha M. Salama, Fathy M. Soliman, Magda M. Fathy, Ali M. El-Halawany and Fatema R. Saber
Posters: J Cancer Sci Ther
DOI: 10.4172/1948-5956.S1.029
Abstract
Aworldwide increasing interest is continuously directed towards searching for cheap tumour inhibitors or cytotoxic compounds from plant origin that might help in chemotherapy and /or chemoprevention of different types of cancer. Eucalyptus cinerea F. Muell. ex Benth. (Silver Dollar Gum, Argyle Apple and Mealy Stingybark) belongs to the family Myrtaceae .Two acyl phloroglucinol compounds namely; Sideroxylonal B (CM 1 ) and macrocarpal A (CM 2 ) were isolated from the Chloroform: Methanol extract (80:20) of the juvenile leaves of Eucalyptus cinerea F. Muell. ex Benth. cultivated in Egypt. Identification of the isolated compounds was established on the basis of physico-chemical properties and 1D and 2D NMR spectroscopy. The two compounds are isolated for the first time from this species.The isolated compounds were tested against three human cancer cell lines; HEP2, CAco and MCF7. Both CM 1 and CM 2 compounds showed moderate to potent cytotoxic activity against the three tested human cancer cell lines with IC 50 7.2, 4, 4.4 and 14.8, 11.4 and 7.8 μg/ml against HEP2, CAco and MCF7 respectively. Results evidenced that CM1 was more potent than CM 2 as a cytotoxic agent against two of the tested cell lines CAco and MCF7 (IC 50 = 4 & 4.4 μg/ml, respectively). Keywords: Eucalyptus cinerea F. Muell. ex Benth, cytotoxic acyl phloroglucinol, Sideroxylonal B and macrocarpal A.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]omicsonline.com

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7