alexa Detection And Genetic Characterization Of Seoul Virus And Other Viruses Borne By Commensal Norway Rats (Rattus Norvegicus) In France
ISSN: 1948-5964

Journal of Antivirals & Antiretrovirals
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

4th World Congress on Virology
October 06-08, 2014 Hilton San Antonio Airport, TX, USA

Michel Pepin, Tatiana Dupinay, Philippe Marianneau, J Lachuer, Anthony R Fooks, Catherine Legras-Lachuer and Lorraine M McElhinney
ScientificTracks Abstracts: J Antivir Antiretrovir
DOI: 10.4172/1948-5964.S1.020
Norway rats (Rattus norvegicus) are prevalent in urban environments, and pose a threat to public health by serving as reservoirs for pathogens that can be transmitted to humans. To identify and assess the prevalence of zoonotic or not zoonotic viruses carried by rats, a next generation sequencing (NGS) method was developed following two steps ; the first one has been dedicated to get an efficient NGS method in order to improve the number of viral reads. For this pilot study, a rat lung sample positive for Seoul virus (SEOV) and previously detected by RT-PCR was used as positive control. SEOV is an hantavirus which can be transmitted to humans primarily via inhalation of aerosolized viruses from contaminated rat urine and faeces. Whilst infected reservoir hosts are asymptomatic, human infections can lead to hemorrhagic fever with renal syndrome (HFRS), with varying degrees of clinical severity. The results of this first study were twice and have permitted (i) to define a robust protocol for viral enrichment and (ii) to obtain the first complete sequence of SEOV detected in France. Phylogenetic analysis supports the inclusion of the Lyon SEOV within lineage 7 along with SEOV strains originating from SE Asia and the previously reported French & Belgian SEOV strains (Dupinay et al, Virol J, 2014). Following on from this pilot study, the virome of a larger number of commensal rats (n=10) has been determined using viral enrichment and NGS previously defined. Results of this second study (analysis in progress) will be presented and discussed.
Michel Pepin has completed his PhD at the age of 26 years from University of Lyon and postdoctoral studies from INRA and ANSES. He is now full professor of Microbiology/Immunology and Infectious Diseases at the National Veterinary School of Lyon (now VetAgroSup).
image PDF   |   image HTML
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version