alexa Development And Application Of Rapid Microbiology Methods In Manufacturing And Control Of Pharmaceuticals
ISSN: 2161-0703

Journal of Medical Microbiology & Diagnosis
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

JOINT EVENT ON 15th International PHARMACEUTICAL MICROBIOLOGY AND BIOTECHNOLOGY CONFERENCE & 10th Annual MEDICAL MICROBIOLOGY SUMMIT & EXPO
June 21-23, 2017 London, UK

Sandra Saiz Balbastre, Montserrat Llagostera, M Angels Calvo, Elisabet Rosell and Carmen Blanes
Laboratorio Reig Jofre, Spain
Autonomous University of Barcelona, Spain
Posters & Accepted Abstracts: J Med Microb Diagn
DOI: 10.4172/2161-0703-C1-006
Abstract
Nowadays, microbiological control in the pharmaceutical industry is mainly based upon incubation of microorganisms to detect contamination. Analyses carried out are very time-consuming and results are poorly accurate due to low sensitivity of the equipment. The main goal of this project is to develop and apply rapid microbiology methods to the routine microbiological control of a pharmaceutical processing plant, under GMP conditions. For this, there are two different objectives to deal with: microbial detection and identification. Firstly, regarding rapid detection, a real-time air-borne microbial detection system has been validated to apply it to an aseptic production chain. This system is based on laser-induced fluorescence, which permits to distinguish between viable and non-viable particles present in the air, as the laser excites esterases in living microorganisms. The advantage of this system in front of the traditional air-sampler is that viable but non culturable microorganisms are also detected, in addition, it is real-time measuring, which makes problem-solving faster. Secondly, a rapid identification system based on MALDI-TOF has been validated, which permits to perform identifications from different contamination sources in less than 24 hours. In addition, a sequencing-based identification method has been developed for specific cases when molecular identification is required by authorities or MALDI-TOF can’t provide an accurate identification. Also, a comparison between both methods has been performed regarding internally detected microorganisms. In conclusion, the setting up of these techniques will improve the sensitivity and quality of microbiological control and will also be time and cost saving for the company.
Biography

Sandra Saiz Balbastre has a degree in Biotechnology from Polytechnic University of Valencia and MSc in Pharmaceutical and Biotechnological Industry from Pompeu Fabra University in Barcelona. Currently, she is pursuing her PhD at a pharmaceutical company Reig Jofre Laboratories in Barcelona in collaboration with Autonomous University of Barcelona, Spain.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords