alexa Diagnosis Of Cancer: A Molecular Approach
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

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4th World Congress on Cancer Science & Therapy
October 20-22, 2014 DoubleTree by Hilton Hotel Chicago-North Shore Conference Center, USA

Pranita Roy
Accepted Abstracts: J Cancer Sci Ther
DOI: 10.4172/1948-5956.S1.035
Abstract
Cancer that has a reputation of a deadly disease all around the world is a broad group of diseases that involves uncontrolled cell growth and proliferation. The best method for its prevention and control is its early diagnosis and treatment. Before molecular diagnostics, scientists relied on the results obtained from biopsies and microscopic examination of affected tissue samples but nowadays molecular diagnosis is emerging as a new and eye opening approach that merges genomics and proteomics for early detection and diagnosis of cancer. Genomics and proteomics tools are used to detect different molecular signatures like genetic and epigenetic signatures, changes in gene expressions, protein biomarker profiles and other metabolite profile changes, which in turn allows to identify the combinations of biomarkers which may detect best the presence or risk of cancer or monitor cancer therapies. Molecular diagnosis uncovers the different changes that occur during the transformation of a normal cell to a tumour cell and capture this information as expression patterns. Robotically printed microarrays, Real time PCR and mi RNAs are widely used techniques for measuring these expression pattern and help researchers to differentiate between a normal and a cancer cell. Molecular diagnosis through proteomics make use of surface enhanced laser desorption/ ionization time of flight mass spectrometry and peptide receptors in mapping of protein patterns that are involved in malignant growth. Nanotechnology is an evolving science that can be successfully used for cancer diagnosis in future. Nanoscale devices quantum dots and carbon nano-tubes can be promising nano-tools for effective measurement of malignancy. All these techniques offer great promise for revolutionizing the diagnosis of cancer. This article recaps some scientific considerations about different relevant molecular diagnostics of cancer and consideration about future challenges.
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