alexa Discovery Of Third Category Of Bionanomotor By Revolution Mechanism Without Rotation And Development Of High Efficient Antibacterial Drug Targeting To Biomotors
ISSN: 2155-9597

Journal of Bacteriology & Parasitology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

2nd International Congress on Bacteriology & Infectious Diseases
November 17-19, 2014 DoubleTree by Hilton Hotel Chicago-North Shore, USA

Peixuan Guo
Accepted Abstracts: J Bacteriol Parasitol
DOI: 10.4172/2155-9597.S1.008
Abstract
Biomotors have been classified into two categories: Linear and rotation motor. For decades, viral DNA-packaging motors have been believed to be the rotation motor. Recently, we discovered a third type of biomotor using the revolution mechanism without rotation. It was found that many dsDNA translocation biomotors use a common revolution mechanism. Rotation is similar to the Earth rotating around its own axis, while revolution is like Earth revolving around the Sun. Acquired drug resistance has become a major threat for bacterial infection. To combat the evolution of drug resistance, new approached in drug design are highly desired. Many biomotors contain a high stoichiometrical number, such as displaying as a hexamer, of components. Our study revealed that drugs targeting a biomotors holding high stoichiometry could cause an exponentially stronger inhibitory effect than targeting complex with low stoichiometry. Bacteria contain many biomotors that can serve as excellent target for the development of high efficient antibacterial drugs. The new methods in drug design reported here can accelerate next generation of potent drugs to remedy drug-resistant of bacterial infection.
Biography
Peixuan Guo received his PhD in Microbiology with training in biophysics from the University of Minnesota in 1987. He obtained Postdoctoral training at NIH before joining Purdue University as an Assistant Professor in 1990, received Tenure in 1993, Full Professor in 1997, and was honored as a Purdue Faculty Scholar in 1998. He was recruited to University of Cincinnati in 2007 as the Dane & Mary Louise Miller Endowed Chair of Biomedical Engineering, and Director of the NIH Nanomedicine Development Center located at the University of Cincinnati. He received the Pfizer Distinguished Faculty Award in 1995; the Purdue Faculty Scholar Award in 1998; the Purdue Seed Award in 2004, 2005, and 2007; the Lions Club Cancer Research Award in 2006; and COV Distinguished Alumni of the University of Minnesota in 2009. He is an Editor or board member of five nanotechnology journals. He was a member of two prominent National Nanotechnology Initiatives sponsored by NIST, NIH, NSF and National Council of Nanotechnology; panelist of DOD medical assessment workshop; Director of one NIH Nanomedicine Development Center from 2006 to 2011, member of the NIH NDC Steering Committee from 2006-2010.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords