Dispersion Of Non-B HIV-1 Subtypes In Northeast Brazil | 24759
Journal of AIDS & Clinical Research
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Brazil comprises 2/3 of people living with HIV in South and Central America, harboring a huge viral diversity, where
subtype B is the most prevalent, followed by subtypes F and C. Various Circulating Recombinant Forms (CRFs) have been
identified in Brazil, like CRF31_BC in the Southern, CRF28_BF, CRF29_BF and CRF_46BF in S?o Paulo; CRF39_BF and
CRF40_BF in Rio de Janeiro. Additionally, multiple minority subtypes and recombinants forms were identified circulating in
the country, such as subtype A, D and recombinants FD, FC, CRF02_AG and the former identification of Unique Recombinant
Forms (URFs) BF and its dissemination in various regions of Brazil. The HIV -1 in Northeast Region also has a large molecular
diversity, with the presence of subtypes B, F, C and D, being mainly characterized by a high percentage of BF recombinants and
subtype F in some areas. It is considered the poorest region of the country with lower Gross National Product (GDP) per capita.
Although the incidence rates of AIDS in the country have stabilized since 2002, in accordance with the Ministry of Health
of Brazil, there is growth in Northeast. Therefore, it is important to extend the knowledge about the molecular epidemiology
of HIV-1 in this region and thus monitor the impact that different viral variants may lead to the spread of the epidemic and
Kledoaldo Oliveira de Lima, 33 years-old, Brazilian, performed his doctoral study at the Federal University of Pernambuco in cooperation with the Federal University
of Par?, emphasizing the theme of the molecular epidemiology of HIV-1. He has published studies on the molecular epidemiology of HIV- 1 and HIV-1 incidence
with biomarkers and currently dedicated to bioinformatics. He works in Federal University of Pernambuco.
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