alexa Does Endocardial Fibroelastosis Of The Left Ventricle Affect Right Ventricular Performance In Fetuses With Hypoplastic Left Heart Syndrome? A Prospective Study Using M Mode, PW And Tissue Doppler Techniques | 64176
ISSN: 2329-6607

Cardiovascular Pharmacology: Open Access
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11th World Congress on Pediatric Cardiology and Congenital Cardiovascular Disease

O Graupner
Technical University of Munich, Germany
Posters & Accepted Abstracts: Cardiovasc Pharm
DOI: 10.4172/2329-6607-C1-003
Abstract
Introduction & Purpose: Myocardial function (MF) of the systemic right ventricle (RV) determines the postnatal course of neonates with hypoplastic left heart syndrome (HLHS). Our study examines, whether the presence of endocardial fibroelastosis of the left ventricle (LV EFE) influences MF of the RV in HLHS fetuses. Materials & Methods: A prospective study was conducted including 10 controls (group 1), 10 HLHS fetuses with (group 2) and 10 without LV EFE (group 3)-all matched for gestational age. M-mode was used to assess tricuspid plane systolic excursion (TAPSE) and the shortening fraction (SF). PW-Doppler and PW-TDI derived velocities were assessed. E/A, E/e', e'/a' ratios and the myocardial performance index (MPI) were calculated. Results: The examination of MF revealed significantly lowers’ the velocities (p<0.05) and higher values for SF in group 2 compared to group 3. ET (ejection time), E wave velocity, E/e’ and SF showed significantly higher values in group 2 compared to group 1. In group 2 a’ velocity increased significantly over gestational age. TAPSE increased during gestation in group 3 but not in group 2. Conclusion: These significant differences in MF between the groups might lend support to the notion of negative ventricularventricular interaction in case of HLHS with LV EFE possibly influencing surgical outcomes.
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