alexa Does N-terminal Pro-brain Natriuretic Peptide Level Predict Prognosis Of Acute Pulmonary Embolism? | 61596
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

16th World Cardiology Congress

Abdelaziz Gomaa and Hanan Radwan
Zagazig University, Egypt
ScientificTracks Abstracts: J Clin Exp Cardiolog
DOI: 10.4172/2155-9880.C1.062
Abstract
Background: Patients with acute Pulmonary Embolism (PE) have a high risk of death. N-terminal pro-brain natriuretic peptide (NT-pro BNP) has emerged as a biomarker for risk assessment in acute PE. Aim: We aimed to detect in hospital prognostic value NT- pro BNP in patients with acute PE. Methods: 64 patients with acute PE were studied. All patients were subjected to ECG, laboratory tests (D-dimer, troponin I, NT-pro BNP), Doppler ultrasound for the venous system of lower limbs, transthoracic echocardiography and 64 multi-slices CT pulmonary angiography. Results: Patients were divided into two groups: group I (22) patients with normal NTpro BNP (<300 pg/ml), and group II (42) patients with elevated NT-pro BNP. Group II had higher incidence of heart failure (28.6% vs. 4.6% P=0.025), impaired kidney function (creatinine 1.7±0.6 vs. 1.1±0.2, P=0.018) and cardiogenic shock (26.2% vs. 0% P=0.014) but lower incidence of chest pain (21.4% vs. 45.5% P=0.04) and lower LV ejection fraction (51.3%±16.9% vs. 67.3%±12.8% P=0.043) compared to group I. Group II had higher treatment with thrombolytic therapy (35.7% vs. 9.1%, P= 0.021) and positive inotropic (35.71% vs. 4.55%, P=0.006), higher need for mechanical ventilation (26.2% vs. 4.55%, P=0.04), longer hospital stay (19.5±10.3 vs. 5.3±4.5, p=0.001) and higher mortality (19.05% vs. 0.0% P=0.042) than group I. Conclusion: Elevated NT-pro BNP levels in patients with PE are associated with worse short term prognosis in terms of higher morbidity and mortality and it could be used as a valuable prognostic parameter and good indicator for the need of more aggressive therapy.
Recent publications:
1. S. Z. Glodhabber, “Pulmonary Embolism. Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine,” 9th Edition, Saunders, 2012.
2. H. Dores, C. Fonseca, S. Leal, I. Rosário, J. Abecasis, J. Monge, M. J. Correia, L. Bronze, A. Leitão, I. Arroja, A. Aleixo and A. Silva, “NT-pro BNP for Risk Stratification of Pulmonary Embolism,” Portuguese Journal of Cardi-ology, Vol. 30, No. 12, 2011, pp. 881-886.
3. M. J. Agterof, R. E. Schutgens, R. J. Snijder, G. Epping,G. Peltenburg, E. F. Posthuma, J. A. Hardeman, R. vander Griend, T. Koster, M. H. Prins and D. H. Biesma, “Out of Hospital Treatment of Acute Pulmonary Embo-lism in Patients with a Low NT-pro BNP Level,” Journal of Thromb Haemost, Vol. 8, No. 6, 2010, pp. 1235-1241. doi:10.1111/j.1538-7836.2010.03831.x
4. R. Cavallazzi, A. Nair, T. Vasu and P. E. Marik, “Natriuretic Peptides in Acute Pulmonary Embolism: A Systematic Review Published Online,” Vol. 34, No. 12, 2008, pp. 2147-2156
5. N. Vuilleumier, M. Righini, A. Perrier, A. Rosset, N. Turck, J. C. Sanchez, H. Bounameaux, G. Le Gal, N. Mensi and D. Hochstrasser, “Correlation between Cardiac Biomarkers and Right Ventricular Enlargement on Chest CT in Non Massive Pulmonary Embolism,” Thombo Re-search, Vol. 121, No. 5, 2008, pp. 617-624. doi:10.1016/j.thromres.2007.07.003
Biography

Abdelaziz Gomaa is a Consultant Interventional Cardiologist at Dallah Hospital Riyadh, KSA and a Lecturer of Cardiology at Zagazig University, Egypt. He is pursuing certified level II training in Cardiac CT (Harefield-London Cardiac CT course) in addition to interventional cardiology practice. His work in Clinical Cardiology gave him good overview of different cardiology emergencies and urgencies.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7