alexa Dynamic Wrist Imaging Using Non-gated 4D Computed Tomographic Scanning
ISSN: 2155-9821

Journal of Bioprocessing & Biotechniques
Open Access

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15th Asia-Pacific Biotechnology Congress
July 20-22, 2017 Melbourne, Australia

Shian-Chao Tay, Ita Suzana Mat Jais and Yoke Rung Wong
Singapore General Hospital, Singapore
Posters & Accepted Abstracts: J Bioprocess Biotech
DOI: 10.4172/2155-9821-C1-013
Abstract
Wrist injuries can lead to static and dynamic instability. Dynamic instability of the wrist often presents with pain but cannot be seen on routine imaging as the instability is only evident during motion. We have previously demonstrated the use of gated 4-dimensional CT (4D CT) to detect and quantify dynamic instability of the wrist. However, the gated CT technique requires wrist motion to be periodic and requires a synchronization signal. The requirement to move in a fixed periodic manner may prove difficult in patients with wrist pain. As such, we developed a truly dynamic CT wrist imaging technique using nongated protocol. Unlike gated CT, non-gated CT imaging does not require periodic and repetitive motion and there is no need for synchronization. To evaluate its efficacy, we scanned five cadaveric wrists during motion. Each cadaveric wrist was mounted on a custom made motion simulator and was scanned while moving in radioulnar deviation at a frequency ranging 10-30 cycles per minute (cpm), through a maximum arc of 30o (10o of radial deviation and 20o ulnar deviation). Data sets were reconstructed at ten different phases of one full motion cycle. We found that we were able to get satisfactory images from the dynamic scan when the motion frequency was less than 15 cpm or at equivalent speed ranging from 9 to 18 mm/s. Motion artifacts were more evident in higher cpm. We have managed to define the boundary motion parameters regard to non-gated 4D CT wrist imaging.
Biography

Shian-Chao Tay is a Senior Consultant in Singapore General Hospital, Department of Hand Surgery. His research interests focus mainly on developing wrist carpal imaging, as well as looking at the kinematics of the wrist. In particular, he is interested in the hysteresis effects in wrist motion and investigating how we can use it to quantify wrist instability. He is also involved in flexor tendon research and actively looking at various repair methods as well as suture knotting techniques and knot locations, to look at both the strength and the friction effects of flexor tendon repairs. He is currently the Director of the Biomechanics Laboratory in Singapore General Hospital.

Email: [email protected]

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