Journal of Aquaculture Research & Development

Effect of Curcuma longa on non-specific immunological profile of Indian snakehead Channa punctatus infected with Aeromonas hydrophila

International Conference on Aquaculture & Fisheries

July 20-22, 2015 Brisbane, Australia

Seema Jain, Manu Varma and Shobhna

Posters-Accepted Abstracts: J Aquac Res Development

Abstract:

Curcumin an orange yellow phytochemical hydrophobic and polyphenolic compound of turmeric (Curcuma longa, Linn.) has been known to be a potent immunomodulatory agent in many animal species. The aim of our study is to evaluate the immunomodulatory properties and disease resistance against the opportunistic pathogen Aeromonas hydrophila in Channa punctatus. Fishes were challenged intraperitoneally with a dose of Aeromonas hydrophila (1�108 cells/ml). Control and Immuno-compromised fishes were given three different doses of curcumin viz., 0.5 mg, 1.0 mg and 1.5 mg/100 gm of body weight respectively. Treated fishes were sacrificed on 3rd, 5th, 7th and 10th day after the dose was given and various non specific immune parameters were assessed viz., Percentage Phagocytosis, Phagocytic index, lysozyme assay, Bactericidal activity and Superoxide anion production. All the non-specific immune parameters were enhanced significantly but the maximum enhancement was seen on the fifth day with the dose of 1.0 mg/100 gm body weight and the same dose also showed maximum disease resistance as compared to other two doses.

Biography :

Seema Jain is currently working in Chaudhary Charan Singh University, India.