alexa Effect Of Lawsonia Inermis Linnaeus Leaf Extracts On Blood Glucose Level In Normal And Streptozotocininduced Diabetic Rats
ISSN: 2155-6156

Journal of Diabetes & Metabolism
Open Access

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14th International Conference and Exhibition on Targeting Diabetes and Novel Therapeutics
October 17-18, 2016 Kuala Lumpur, Malaysia

Widyawati T, Pane Y S, Hasibuan S S and Satria D
University of Sumatera Utara, Indonesia
ScientificTracks Abstracts: J Diabetes Metab
DOI: 10.4172/2155-6156.C1.057
Abstract
Lawsonia inermis Linnaeus is one of the plants commonly used in Indonesian community for the treatment of different diseases. The anti-diabetic activity was evaluated by determining whether the extracts lowered the blood glucose level BGL0 of normal rats (hypoglycemic test) or lowered BGL of streptozotocin-induced diabetic rats (SDR). Dried powdered L. inermis leaves were extracted serially with n-hexane (HE), ethylacetate (EAE), ethanol (EE), water1(WE1) and water2 (WE2). Hypoglycemic in normal rats showed only HE significantly reduce fasting BGL at 3 h observation. However, in antihyperglycemic test in SDR, single-dose administration of the extracts showed that only EAE reduced BGL signficantly at 3 h observation. The present work conclude that EAE is the most active extract as antihyperglycemic.
Biography

Widyawati T is a Lecturer at Medical Faculty, University of Sumatera Utara since 2003. Currently, she is pursuing her PhD at Pharmaceutical Sciences University Sains Malaysia and has submitted her final thesis.

Email: [email protected]

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