alexa Effects Of Histone Deacetylase Inhibitors On Anti Neo Plastic Activity
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

14th World Cancer & Anti-Cancer Therapy Convention
November 21-23, 2016 Dubai, UAE

Juhi Tiwari, Smriti Rai, Rini Parashar and Yuvraj Jain
Jayoti Vidyapeeth Women’s University, India
ScientificTracks Abstracts: J Cancer Sci Ther
DOI: 10.4172/1948-5956.C1.093
Abstract
Histone deacetylase inhibitors are a new class of drug that interferes with the function of histone deacetylase . These drugs are being used in neurology and psychiatry as a mood stabilizers and as a anti epileptics. More recently they are being investigated as possible treatments of cancer and inflammatory diseases. Histone deacetylase inhibitors affects the gene expression by hyperacetylation of histone. To carry out gene expression,a cell must control the coiling and uncoiling of D.N.A around histones. This is accomplished with the assistance of histone acetyl transferase which acetylate the lysine residue in core histone leading to a less compact and transcriptionally active chromatin and on the converse, the action of histone deacetylase which remove the acetyl group from the lysine residue leading to the formation of a condensed and transcriptionally silenced chromatin. Reversible modification of the terminal tails of core hitones constitute the major epigenetic mechanism for remodeling higher order chromatin structure and controlling gene expression . Histone deacetylase inhibitors block this action and can result in hyperacetylation of histone thereby affecting gene expressions.
Biography

Juhi Tiwari has completed her M.Pharm in Pharmacology at the age of 24 years from Jayoti Vidyapeeth Women’s University and published a two research paper on anti pyretic and anti urolithiatic effect and two review article on Autism and on anti neoplastic agents in Pharmaceutical regulatory affairs and in World Congress on Cancer therapy and was invited as a speaker international conference 2015.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords